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For postmenopausal women with HR+ breast cancer
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FAQs About Taking ARIMIDEX

Answers to frequently asked questions for anyone taking, or considering taking, ARIMIDEX. Always speak with your doctor or health care provider before making any decisions about taking ARIMIDEX.

If you are postmenopausal and have been diagnosed with hormone receptor-positive early breast cancer, and have recently undergone surgery with radiation, and/or chemotherapy, ARIMIDEX may be right for you. Discuss all your treatment options with your doctor.

In the early breast cancer clinical trial, the most common side effects seen with ARIMIDEX included hot flashes, joint symptoms (including arthritis and arthralgia), weakness, mood changes, pain, back pain, sore throat, nausea and vomiting, rash, depression, high blood pressure, osteoporosis, fractures,* swelling of arms/legs, insomnia, and headache.

*Fractures (including fractures of the spine, hip, and wrist) occurred more frequently with ARIMIDEX than with tamoxifen (10% vs 7%).

You should also know that:

  • You should speak with your doctor about any bone tests needed to determine your risk for osteoporosis
  • ARIMIDEX should not be taken with tamoxifen or with estrogen-containing therapies

Find out more about possible side effects of ARIMIDEX

Do not take ARIMIDEX if you:

  • Are pregnant, think you may be pregnant, or plan to become pregnant
  • Have not finished menopause (are premenopausal)
  • Are allergic to any of the ingredients in ARIMIDEX. See the full Prescribing Information for a complete list

ARIMIDEX is a hormonal treatment (also called hormonal therapy), not a cytotoxic chemotherapy. It works by reducing the amount of estrogen produced by your body. For more details, see How ARIMIDEX Works.

The dose for ARIMIDEX is 1 small tablet that you swallow once a day. Take ARIMIDEX exactly as prescribed by your doctor.

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose. Take your next regularly scheduled dose. Learn more about ARIMIDEX Dosing Information.

Take ARIMIDEX until your doctor tells you to stop. Participants in the early breast cancer clinical trial, called the ATAC breast cancer clinical trial, were treated for 5 years.

View Prescribing Information

Important Safety Information About ARIMIDEX

  • Prescription ARIMIDEX is only for postmenopausal women. ARIMIDEX should not be taken if you are pregnant because it may harm your unborn child. Do not take ARIMIDEX if you are allergic to any of its ingredients
  • Based on information from a study in patients with early breast cancer, women with a history of blockages in heart arteries (ischemic heart disease) who take ARIMIDEX may have a slight increase in this type of heart disease compared to similar patients who take tamoxifen
  • ARIMIDEX can cause bone softening/weakening (osteoporosis) increasing the chance of fractures. In a clinical study in early breast cancer, there were more fractures (including fractures of the spine, hip, and wrist) with ARIMIDEX (10%) than with tamoxifen (7%)
  • In a clinical study in early breast cancer, some patients taking ARIMIDEX had an increase in cholesterol. Skin reactions, allergic reactions, and changes in blood tests of liver function have also been reported
  • In the early breast cancer clinical trial, the most common side effects seen with ARIMIDEX include hot flashes, joint symptoms (including arthritis and arthralgia), weakness, mood changes, pain, back pain, sore throat, nausea and vomiting, rash, depression, high blood pressure, osteoporosis, fractures, swelling of arms/legs, insomnia, and headache
  • In advanced breast cancer trials, the most common side effects seen with ARIMIDEX versus tamoxifen include hot flashes, nausea, decreased energy and weakness, pain, back pain, headache, bone pain, increased cough, shortness of breath, sore throat, and swelling of arms and legs. Joint pain/stiffness has been reported in association with the use of ARIMIDEX
  • ARIMIDEX should not be taken with tamoxifen or estrogen-containing therapies

Approved Uses for ARIMIDEX

ARIMIDEX is approved for adjuvant treatment (treatment following surgery with or without radiation) of postmenopausal women with hormone receptor-positive early breast cancer.

ARIMIDEX is approved for the initial treatment of postmenopausal women with hormone receptor-positive or hormone receptor-unknown locally advanced or metastatic breast cancer and for the treatment of postmenopausal women with advanced breast cancer that has progressed following treatment with tamoxifen. Patients with hormone receptor-negative disease and patients who did not previously respond to tamoxifen therapy rarely responded to ARIMIDEX.

For more information, see your doctor. Please see full Prescribing Information.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.FDA.gov/medwatch or call 1-800-FDA-1088.

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The information on this Web site should not take the place of talking with your doctor or health care professional. If you have any questions about your condition, or if you would like more information about ARIMIDEX, talk to your doctor or pharmacist. Only you and your health care professional can decide if ARIMIDEX is right for you.